The American healthcare system continues its transformational journey into 2016 and beyond, with fresh evidence of the ongoing impact of the Affordable Care Act, as well as continued shifts in the economic and organizational models of healthcare. Providers, payers, regulators and consumers are each adjusting their strategies, policies, and behaviors to an increasingly complex —and zero-sum—environment. It's Game On, where the era of collaboration is giving way to sophisticated competitive strategies to gain or retain market share, attract and retain consumers, and control as much of the healthcare dollar as possible.

In 2013, Manatt Health first identified "10 Megatrends Reinventing Healthcare" that would shape the healthcare marketplace across the next decade. In a new white paper, we examine these trends two years later—and reveal how they are continuing to drive changes in behaviors, expectations and results across the healthcare sector. For 2016, we have also added an eleventh trend: Focus on the Whole Person, bookending our first trend: Consumers Take Charge. This powerful trend recognizes that leading-edge healthcare stakeholders at every level are beginning to take an integrated approach to medical, behavioral, public health and social influences on the health of populations and individuals.