As well as these vaccines, there are many more on the way – as of 28 December 2021, there were 137 vaccines in clinical development and 194 vaccines in pre-clinical development. Although the majority are injectable (84%), two dose (61%) vaccines, they are based on a wide range of different platforms – protein subunit (35%), RNA (17%), non-replicating viral vector (15%), inactivated virus (13%) and DNA (11%).
Vaccination
In the UK, as of 28 December 2021, over 51 million and 47 million people have received a first and second dose respectively. In addition, over 33 million people have received a booster dose. This equates to about 82.3% of the UK population (over aged 12) being double jabbed, with 57.5% also having had a booster. Many countries have also carried out successful vaccination programmes and fully vaccinated over 70% of their population, including Germany, France, Italy, Spain, Portugal, Finland, Sweden, Norway, Denmark, Singapore, China, Japan, the UAE, Australia and New Zealand. Unfortunately, the success of the vaccination efforts in these countries has not been capable of replication worldwide.
As I mentioned previously, new Regulation 247A of the HMRs allowed a wider range of personnel to administer vaccines and, due to this change, I have the privilege of being involved in the NHS Covid-19 vaccination programme as a St John Ambulance volunteer vaccinator. One thing that has particularly struck me is the amount of planning, and additional people and resources, needed to deliver a safe and efficient mass vaccination programme.
As of 13 December 2021, only 20 African countries had fully vaccinated at least 10% of their population. Only six of those countries have hit the year-end target of fully vaccinating 40% of their population. Only two countries (Mauritius and the Seychelles) have reached the 70% threshold that is considered necessary. Although many African countries are successfully building on their previous experiences of vaccination campaigns (for example, measles, polio and ebola), many do not have the funds needed to cover operational costs and many face shortages of staff and necessary commodities.
Globally, there has now been over 280 million confirmed cases of COVID-19 and nearly five and a half million reported deaths. Higher-income countries and global organisations must step up and ensure lower-income countries can address the specific challenges they face to deliver successful vaccination programmes. Not just for morality, but also to prevent the virus being given space to mutate – possibly into more dangerous variants. As the WHO has said consistently - ‘it’s not vaccines that will stop the pandemic, it’s vaccination.’
Sources:
World Health Organisation
GOV.UK (Coronavirus)
World Health Organization - Africa
WHO Coronavirus (COVID-19) Dashboard
COVID-19 Vaccine Tracker
World Health Organization - Regulation and Prequalification
European Medicines Agency
U.S. FDA
Allen & Overy - Covid-19 coronavirus – the UK’s preparation for a vaccine
UK Health Security Agency
BBC News
World Health Organization - Africa