The UK has voted to leave the European Union. This will not affect the UK’s position as one of the most important IP jurisdictions in Europe. However, leaving the European Union will have an impact on substantive IP law in the UK. The extent of the changes to UK IP law will depend on the future relationship that the UK has with the European Union. The forthcoming Unified Patent Court has also been affected and its introduction will now be delayed, with the length of the delay depending on the extent of political will to push it forward quickly. We discuss here the effect of Brexit on UK IP law and the Unified Patent Court, and the practical steps that you should consider taking in light of this momentous decision.